P Antibody (PACO34008)
- SKU:
- PACO34008
- Product Type:
- Antibody
- Reactivity:
- Virus
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | P Antibody (PACO34008) |
| Antibody SKU: | PACO34008 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Rabies virus |
| Immunogen: | Recombinant Rabies virus Phosphoprotein protein (1-297AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: P antibody at 2µg/ml. Lane 1: Rabies virus Phosphoprotein protein at 1µg. Lane 2: Rabies virus Phosphoprotein protein at 0.1µg. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 34, 32, 28, 26, 25 kDa. Observed band size: 34 kDa. |
| Background: | Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-α and IFN-β signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body |
| Synonyms: | Phosphoprotein (Protein P) (Protein M1), P |
| UniProt Protein Function: | Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P69480 |
| NCBI GenInfo Identifier: | 61237514 |
| NCBI Gene ID: | |
| NCBI Accession: | P69480.1 |
| UniProt Secondary Accession: | P69480,P22559 |
| UniProt Related Accession: | P69480 |
| Molecular Weight: | |
| NCBI Full Name: | Phosphoprotein |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Phosphoprotein |
| UniProt Synonym Protein Names: | Protein M1 |
| Protein Family: | |
| UniProt Gene Name: | P |
| UniProt Entry Name: | PHOSP_RABVM |
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