OXER1 Antibody (PACO55222)
- SKU:
- PACO55222
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | OXER1 Antibody (PACO55222) |
| Antibody SKU: | PACO55222 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Rat |
| Immunogen: | Recombinant Human Oxoeicosanoid receptor 1 protein (1-97AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: K562 whole cell lysate, HepG2 whole cell lysate, HEK293 whole cell lysate, Rat lung tissue. All lanes: OXER1 antibody at 2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 46 kDa. Observed band size: 46 kDa. |
 | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO55222 at dilution of 1:100. |
| Background: | Receptor for eicosanoids and polyunsaturated fatty acid, such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid, (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid, (5(S)-HPETE) and arachidonic acid, Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. |
| Synonyms: | Oxoeicosanoid receptor 1 (5-oxo-ETE G-protein coupled receptor) (G-protein coupled receptor 170) (G-protein coupled receptor R527) (G-protein coupled receptor TG1019), OXER1, GPR170 TG1019 |
| UniProt Protein Function: | OXER1: Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1Chromosomal Location of Human Ortholog: 2p21Cellular Component: integral to membrane; plasma membraneMolecular Function: 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding; G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; regulation of cAMP biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8TDS5 |
| NCBI GenInfo Identifier: | 74762623 |
| NCBI Gene ID: | 165140 |
| NCBI Accession: | Q8TDS5.1 |
| UniProt Secondary Accession: | Q8TDS5,Q86WP7, Q8NGW4 |
| UniProt Related Accession: | Q8TDS5 |
| Molecular Weight: | 45,811 Da |
| NCBI Full Name: | Oxoeicosanoid receptor 1 |
| NCBI Synonym Full Names: | oxoeicosanoid (OXE) receptor 1 |
| NCBI Official Symbol: | OXER1 |
| NCBI Official Synonym Symbols: | GPCR; GPR170; TG1019 |
| NCBI Protein Information: | oxoeicosanoid receptor 1 |
| UniProt Protein Name: | Oxoeicosanoid receptor 1 |
| UniProt Synonym Protein Names: | 5-oxo-ETE G-protein coupled receptor; G-protein coupled receptor 170; G-protein coupled receptor R527; G-protein coupled receptor TG1019 |
| Protein Family: | Oxoeicosanoid receptor |
| UniProt Gene Name: | OXER1 |
| UniProt Entry Name: | OXER1_HUMAN |
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