Description
Product Name: | OSTN Antibody |
Product Code: | PACO64881 |
Size: | 50µL |
Target Names: | OSTN |
Species Reactivity: | Human |
Host Species: | Rabbit |
Antigen Species: | Human |
Tested Applications: | ELISA, IHC; Recommended dilution: IHC:1:100-1:500 |
Isotype: | IgG |
Clone ID: | N/A |
Conjugate: | Non-conjugated |
Clonality: | Polyclonal |
Antigen: | Recombinant Human Osteocrin protein (28-133aa) |
Form: | Liquid |
Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Storage: | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Aliases: | Osteocrin (Musclin) [Cleaved into: Processed Osteocrin], OSTN |
Uniprot ID: | P61366 |
Background: | Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience (PubMed:27830782). Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex (PubMed:27830782). Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity). |
Research Area: | Stem Cells |