ONECUT2 Antibody (PACO49834)
- SKU:
- PACO49834
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ONECUT2 Antibody (PACO49834) |
| Antibody SKU: | PACO49834 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human One cut domain family member 2 protein (214-331AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: A549 whole cell lysate, HepG2 whole cell lysate, Hela whole cell lysate. All lanes: ONECUT2 antibody at 2.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 55 kDa. Observed band size: 55 kDa.. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO49834 at dilution of 1:100. |
| Background: | Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B. |
| Synonyms: | One cut domain family member 2 (Hepatocyte nuclear factor 6-beta) (HNF-6-beta) (One cut homeobox 2) (Transcription factor ONECUT-2) (OC-2), ONECUT2, HNF6B |
| UniProt Protein Function: | ONECUT2: Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B. Belongs to the CUT homeobox family.Protein type: Cell development/differentiation; DNA-binding; Transcription factor; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 18q21.31Cellular Component: actin cytoskeleton; nucleoplasm; nucleusBiological Process: cell differentiation; organ morphogenesis; positive regulation of transcription from RNA polymerase II promoter |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95948 |
| NCBI GenInfo Identifier: | 294862454 |
| NCBI Gene ID: | 9480 |
| NCBI Accession: | O95948.2 |
| UniProt Secondary Accession: | O95948 |
| UniProt Related Accession: | O95948 |
| Molecular Weight: | 54,303 Da |
| NCBI Full Name: | One cut domain family member 2 |
| NCBI Synonym Full Names: | one cut homeobox 2 |
| NCBI Official Symbol: | ONECUT2 |
| NCBI Official Synonym Symbols: | OC2; OC-2 |
| NCBI Protein Information: | one cut domain family member 2 |
| UniProt Protein Name: | One cut domain family member 2 |
| UniProt Synonym Protein Names: | Hepatocyte nuclear factor 6-beta; HNF-6-beta; One cut homeobox 2; Transcription factor ONECUT-2; OC-2 |
| Protein Family: | One cut domain family |
| UniProt Gene Name: | ONECUT2 |
| UniProt Entry Name: | ONEC2_HUMAN |
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