OLFML3 Antibody (PACO52850)
- SKU:
- PACO52850
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | OLFML3 Antibody (PACO52850) |
| Antibody SKU: | PACO52850 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Rat |
| Immunogen: | Recombinant Human Olfactomedin-like protein 3 protein (201-406AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Rat skeletal muscle tissue. All lanes: OLFML3 antibody at 2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 47, 44, 33 kDa. Observed band size: 47 kDa. |
 | Immunohistochemistry of paraffin-embedded human liver tissue using PACO52850 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO52850 at dilution of 1:100. |
| Background: | Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes. |
| Synonyms: | Olfactomedin-like protein 3 (HNOEL-iso) (hOLF44), OLFML3 |
| UniProt Protein Function: | OLFML3: Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation. May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes. Belongs to the OLFML3 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 1p13.2 |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NRN5 |
| NCBI GenInfo Identifier: | 37999795 |
| NCBI Gene ID: | 56944 |
| NCBI Accession: | Q9NRN5.1 |
| UniProt Secondary Accession: | Q9NRN5,Q53FR1, Q53HV9, Q5SQL6, Q69AX9, Q8NBJ2 |
| UniProt Related Accession: | Q9NRN5 |
| Molecular Weight: | 32,451 Da |
| NCBI Full Name: | Olfactomedin-like protein 3 |
| NCBI Synonym Full Names: | olfactomedin like 3 |
| NCBI Official Symbol: | OLFML3 |
| NCBI Official Synonym Symbols: | OLF44; HNOEL-iso |
| NCBI Protein Information: | olfactomedin-like protein 3 |
| UniProt Protein Name: | Olfactomedin-like protein 3 |
| UniProt Synonym Protein Names: | HNOEL-iso; hOLF44 |
| Protein Family: | Olfactomedin-like protein |
| UniProt Gene Name: | OLFML3 |
| UniProt Entry Name: | OLFL3_HUMAN |
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