OIP5 Polyclonal Antibody (CAB11611)
- SKU:
- CAB11611
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | OIP5 Polyclonal Antibody |
| Product Code: | CAB11611 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | Chromosome, Nucleus, centromere |
The protein encoded by this gene localizes to centromeres, where it is essential for recruitment of CENP-A through the mediator Holliday junction recognition protein. Expression of this gene is upregulated in several cancers, making it a putative therapeutic target. Two transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-229 of human OIP5 (NP_009211.1). |
| Sequence: | MAAQP LRHRS RCATP PRGDF CGGTE RAIDQ ASFTT SMEWD TQVVK GSSPL GPAGL GAEEP AAGPQ LPSWL QPERC AVFQC AQCHA VLADS VHLAW DLSRS LGAVV FSRVT NNVVL EAPFL VGIEG SLKGS TYNLL FCGSC GIPVG FHLYS THAAL AALRG HFCLS SDKMV CYLLK TKAIV NASEM DIQNV PLSEK IAELK EKIVL THNRL KSLMK ILSEV TPDQS KPEN |
| Synonyms: | CT86, MIS18B, LINT-25, MIS18beta, hMIS18beta, 5730547N13Rik |
| Calculated MW: | 25kDa |
| Observed MW: | Refer to Figures |
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