OFCC1 Antibody (PACO37642)
- SKU:
- PACO37642
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | OFCC1 Antibody (PACO37642) |
| Antibody SKU: | PACO37642 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Orofacial cleft 1 candidate gene 1 protein (3-231AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: OFCC1 antibody at 2µg/ml + Mouse gonadal tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 27, 32, 21, 14, 16 kDa. Observed band size: 27 kDa. |
| Background: | This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG). |
| Synonyms: | Orofacial cleft 1 candidate gene 1 protein (Orofacial clefting chromosomal breakpoint region candidate 1 protein), OFCC1, MRDS1 |
| UniProt Protein Function: | OFCC1: A chromosomal aberration involving OFCC1 is found in patients with orofacial cleft. 5 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 6p24.3Molecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IZS5 |
| NCBI GenInfo Identifier: | 74750797 |
| NCBI Gene ID: | |
| NCBI Accession: | Q8IZS5.1 |
| UniProt Secondary Accession: | Q8IZS5,Q7Z2X5, Q8IUL6, Q8IUM1, Q8IZR9, Q8IZS1, Q8IZS3 |
| UniProt Related Accession: | Q8IZS5 |
| Molecular Weight: | 15,709 Da |
| NCBI Full Name: | Orofacial cleft 1 candidate gene 1 protein |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Orofacial cleft 1 candidate gene 1 protein |
| UniProt Synonym Protein Names: | Orofacial clefting chromosomal breakpoint region candidate 1 protein |
| Protein Family: | Orofacial cleft 1 candidate gene 1 protein |
| UniProt Gene Name: | OFCC1 |
| UniProt Entry Name: | OFCC1_HUMAN |
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