OCT2 Transcription Factor Activity Assay
- SKU:
- TFAB00150
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- OCT2
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
Description
| Product Name: | OCT2 Transcription Factor Activity Assay |
| Product Code: | TFAB00150 |
| Target: | OCT2 |
| Synonyms: | Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Oct-2, Octamer-binding transcription factor 2, OTF-2 |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie Oct2 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | Oct2: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. Belongs to the POU transcription factor family. Class- 2 subfamily. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: cytoplasm; nucleus Molecular Function:protein domain specific binding; sequence-specific DNA binding; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; immunoglobulin secretion during immune response; mature B cell differentiation; positive regulation of transcription, DNA-dependent; cell maturation; humoral immune response |
| NCBI Summary: | The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | P09086 |
| NCBI GenInfo Identifier: | 123402 |
| NCBI Gene ID: | 5452 |
| NCBI Accession: | P09086.3 |
| UniProt Secondary Accession: | P09086,Q16648, Q7M4M8, Q9BRS4, |
| UniProt Related Accession: | P09086 |
| Molecular Weight: | 400 |
| NCBI Full Name: | POU domain, class 2, transcription factor 2 |
| NCBI Synonym Full Names: | POU class 2 homeobox 2 |
| NCBI Official Symbol: | POU2F2 |
| NCBI Official Synonym Symbols: | OCT2; OTF2; Oct-2 |
| NCBI Protein Information: | POU domain, class 2, transcription factor 2; OTF-2; homeobox protein; octamer-binding protein 2; octamer-binding transcription factor 2; lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 |
| UniProt Protein Name: | POU domain, class 2, transcription factor 2 |
| UniProt Synonym Protein Names: | Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2 |
| Protein Family: | POU domain, class 2, transcription factor |
| UniProt Gene Name: | POU2F2 |
| UniProt Entry Name: | PO2F2_HUMAN |
