Occludin Monoclonal Antibody
- SKU:
- CAB24601
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | Occludin Monoclonal Antibody |
| Product Code: | CAB24601 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63373 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse liver |
| Cellular Location: | Cell junction, Membrane, Multi-pass membrane protein, tight junction |
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 405-522AA of human Occludin (NP_001192183.1). |
| Sequence: | GGESC DELEE DWIRE YPPIT SDQQR QLYKR NFDTG LQEYK SLQSE LDEIN KELSR LDKEL DDYRE ESEEY MAAAD EYNRL KQVKG SADYK SKKNH CKQLK SKLSH IKKMV GDYDR QKT |
| Synonyms: | BLCPMG, PTORCH1, PPP1R115 |
| Calculated MW: | 59kDa |
| Observed MW: | 65kDa |
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