NXF3 Antibody (PACO28682)
- SKU:
- PACO28682
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NXF3 Antibody (PACO28682) |
| Antibody SKU: | PACO28682 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Nuclear RNA export factor 3 protein (1-531AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human heart tissue using PACO28682 at dilution of 1:100. |
 | Immunofluorescent analysis of MCF-7 cells using PACO28682 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | May function as a tissue-specific nuclear mRNA export factor. |
| Synonyms: | Nuclear RNA export factor 3 (TAP-like protein 3) (TAPL-3), NXF3, TAPL3 |
| UniProt Protein Function: | NXF3: May function as a tissue-specific nuclear mRNA export factor. Belongs to the NXF family.Chromosomal Location of Human Ortholog: Xq22Cellular Component: cytoplasm; nuclear RNA export factor complex; nucleoplasm; nucleusMolecular Function: mRNA binding; nucleotide binding; protein bindingBiological Process: mRNA export from nucleus; poly(A)+ mRNA export from nucleus |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9H4D5 |
| NCBI GenInfo Identifier: | 20455187 |
| NCBI Gene ID: | 56000 |
| NCBI Accession: | Q9H4D5.1 |
| UniProt Secondary Accession: | Q9H4D5,Q5H9I1, Q9H1A9, B4DYS7 |
| UniProt Related Accession: | Q9H4D5 |
| Molecular Weight: | 26,653 Da |
| NCBI Full Name: | Nuclear RNA export factor 3 |
| NCBI Synonym Full Names: | nuclear RNA export factor 3 |
| NCBI Official Symbol: | NXF3 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | nuclear RNA export factor 3 |
| UniProt Protein Name: | Nuclear RNA export factor 3 |
| UniProt Synonym Protein Names: | TAP-like protein 3; TAPL-3 |
| Protein Family: | Nuclear RNA export factor |
| UniProt Gene Name: | NXF3 |
| UniProt Entry Name: | NXF3_HUMAN |
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