NUGGC Antibody (PACO62479)
- SKU:
- PACO62479
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NUGGC Antibody (PACO62479) |
| Antibody SKU: | PACO62479 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Nuclear GTPase SLIP-GC protein (1-228AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: HepG2 whole cell lysate, K562 whole cell lysate, SH-SY5Y whole cell lysate, HL-60 whole cell lysate. All lanes: NUGGC antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 92 kDa. Observed band size: 92 kDa. |
| Background: | Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA. Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity). |
| Synonyms: | Nuclear GTPase SLIP-GC (EC 3.6.1) (Speckled-like pattern in the germinal center), NUGGC, C8orf80 |
| UniProt Protein Function: | NUGGC: Plays a role as replication-related GTPase protein in germinal center B-cell.Protein type: EC 3.6.1.-Chromosomal Location of Human Ortholog: 8p21.1 |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q68CJ6 |
| NCBI GenInfo Identifier: | 292495064 |
| NCBI Gene ID: | 389643 |
| NCBI Accession: | Q68CJ6.3 |
| UniProt Secondary Accession: | Q68CJ6,Q6ZP73 |
| UniProt Related Accession: | Q68CJ6 |
| Molecular Weight: | 91,132 Da |
| NCBI Full Name: | Nuclear GTPase SLIP-GC |
| NCBI Synonym Full Names: | nuclear GTPase, germinal center associated |
| NCBI Official Symbol: | NUGGC |
| NCBI Official Synonym Symbols: | C8orf80; SLIP-GC; HMFN0672 |
| NCBI Protein Information: | nuclear GTPase SLIP-GC |
| UniProt Protein Name: | Nuclear GTPase SLIP-GC |
| UniProt Synonym Protein Names: | Speckled-like pattern in the germinal center |
| Protein Family: | Nuclear GTPase |
| UniProt Gene Name: | NUGGC |
| UniProt Entry Name: | SLIP_HUMAN |
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