NUDT14 Antibody (PACO28658)
- SKU:
- PACO28658
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NUDT14 Antibody (PACO28658) |
| Antibody SKU: | PACO28658 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Uridine diphosphate glucose pyrophosphatase protein (1-222AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose. |
| Synonyms: | Uridine diphosphate glucose pyrophosphatase (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 14) (Nudix motif 14), NUDT14, UGPP |
| UniProt Protein Function: | NUDT14: Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP- mannose. Belongs to the Nudix hydrolase family.Protein type: Hydrolase; EC 3.6.1.45Chromosomal Location of Human Ortholog: 14q32.33Cellular Component: cytoplasmMolecular Function: protein binding; ADP-ribose diphosphatase activity; metal ion binding; UDP-sugar diphosphatase activityBiological Process: metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | UDP-glucose (UDPG) acts as the sugar donor in numerous glycosylation reactions, including those involved in the production of glycogen. NUDT14 is a UDPG pyrophosphatase (EC 3.6.1.45) that hydrolyzes UDPG to produce glucose 1-phosphate and UMP (Yagi et al., 2003 [PubMed 12429023]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | O95848 |
| NCBI GenInfo Identifier: | 37594467 |
| NCBI Gene ID: | 256281 |
| NCBI Accession: | NP_803877.2 |
| UniProt Secondary Accession: | O95848,Q86SJ8 |
| UniProt Related Accession: | O95848 |
| Molecular Weight: | 24,118 Da |
| NCBI Full Name: | uridine diphosphate glucose pyrophosphatase |
| NCBI Synonym Full Names: | nudix (nucleoside diphosphate linked moiety X)-type motif 14 |
| NCBI Official Symbol: | NUDT14 |
| NCBI Official Synonym Symbols: | UGPP; UGPPase |
| NCBI Protein Information: | uridine diphosphate glucose pyrophosphatase; UDPG pyrophosphatase; UDP-sugar diphosphatase |
| UniProt Protein Name: | Uridine diphosphate glucose pyrophosphatase |
| UniProt Synonym Protein Names: | Nucleoside diphosphate-linked moiety X motif 14; Nudix motif 14 |
| Protein Family: | Nudix hydrolase |
| UniProt Gene Name: | NUDT14 |
| UniProt Entry Name: | NUD14_HUMAN |
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