Description
| Antibody Name: | NT5C1B Antibody (PACO22296) |
| Antibody SKU: | PACO22296 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:100-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human NT5C1B. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunofluorescence analysis of A549 cells, using NT5C1B antibody. |
| Background: | Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels By similarity. |
| Synonyms: | 5 nucleotidase; cytosolic IB; 5NT1B; AIRP; EC 3.1.3.5 |
| UniProt Protein Function: | NT5C1B: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels. Belongs to the 5'-nucleotidase type 3 family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Nucleotide Metabolism - pyrimidine; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 3.1.3.5; Nucleotide Metabolism - purine; HydrolaseChromosomal Location of Human Ortholog: 2p24.2Cellular Component: cytosol; nucleusMolecular Function: 5'-nucleotidase activity; magnesium ion binding; nucleotide bindingBiological Process: dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; purine nucleotide catabolic process; purine base metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | Cytosolic 5-prime nucleotidases, such as NT5C1B, catalyze production of adenosine, which regulates diverse physiologic processes (Sala-Newby and Newby, 2001 [PubMed 11690631]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q96P26 |
| NCBI GenInfo Identifier: | 50593110 |
| NCBI Gene ID: | 93034 |
| NCBI Accession: | NP_001002006.1 |
| UniProt Secondary Accession: | Q96P26 |
| UniProt Related Accession: | Q96P26 |
| Molecular Weight: | |
| NCBI Full Name: | cytosolic 5'-nucleotidase 1B isoform 1 |
| NCBI Synonym Full Names: | 5'-nucleotidase, cytosolic IB |
| NCBI Official Symbol: | NT5C1B |
| NCBI Official Synonym Symbols: | AIRP; CN1B; CN-IB |
| NCBI Protein Information: | cytosolic 5'-nucleotidase 1B |
| UniProt Protein Name: | Cytosolic 5'-nucleotidase 1B |
| UniProt Synonym Protein Names: | Autoimmune infertility-related protein; Cytosolic 5'-nucleotidase IB |
| Protein Family: | |
| UniProt Gene Name: | NT5C1B |
| UniProt Entry Name: | 5NT1B_HUMAN |
| Antibodies |
| NT5C1B Antibody (PACO06027) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
