Description
Antibody Name: | NT5C1A Antibody (PACO40734) |
Antibody SKU: | PACO40734 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:10-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Cytosolic 5'-nucleotidase 1A protein (1-368AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO40734 at dilution of 1:10. |
![]() | Immunofluorescent analysis of A549 cells using PACO40734 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia. |
Synonyms: | Cytosolic 5'-nucleotidase 1A (cN1A) (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IA) (cN-I) (cN-IA), NT5C1A |
UniProt Protein Function: | NT5C1A: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia. Belongs to the 5'-nucleotidase type 3 family.Protein type: Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 3.1.3.5; Phosphatase (non-protein)Chromosomal Location of Human Ortholog: 1p34.3-p33Cellular Component: cytosolMolecular Function: 5'-nucleotidase activity; magnesium ion binding; nucleotide bindingBiological Process: adenosine metabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; nucleoside metabolic process; purine base metabolic process; purine nucleoside monophosphate catabolic process; purine nucleotide catabolic process; pyrimidine base metabolic process; pyrimidine nucleoside catabolic process |
UniProt Protein Details: | |
NCBI Summary: | Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9BXI3 |
NCBI GenInfo Identifier: | 47116736 |
NCBI Gene ID: | 84618 |
NCBI Accession: | Q9BXI3.1 |
UniProt Secondary Accession: | Q9BXI3,Q3SYB9, Q5TG98, Q9BWT8 |
UniProt Related Accession: | Q9BXI3 |
Molecular Weight: | |
NCBI Full Name: | Cytosolic 5'-nucleotidase 1A |
NCBI Synonym Full Names: | 5'-nucleotidase, cytosolic IA |
NCBI Official Symbol: | NT5C1A |
NCBI Official Synonym Symbols: | CN1; CNI; CN-I; CN1A; CN-IA |
NCBI Protein Information: | cytosolic 5'-nucleotidase 1A |
UniProt Protein Name: | Cytosolic 5'-nucleotidase 1A |
UniProt Synonym Protein Names: | Cytosolic 5'-nucleotidase IA; cN-I; cN-IA |
Protein Family: | Cytosolic 5'-nucleotidase |
UniProt Gene Name: | NT5C1A |
UniProt Entry Name: | 5NT1A_HUMAN |
Antibodies |
NT5C1A Antibody (PACO06024) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |