Description
| Antibody Name: | NT5C1A Antibody (PACO23425) |
| Antibody SKU: | PACO23425 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human NT5C1A. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from MCF-7 cells and HepG2 cells, using NT5C1A antibody. |
![]() | Immunofluorescence analysis of A549 cells, using NT5C1A antibody. |
| Background: | Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia. |
| Synonyms: | nucleotidase; cytosolic IA; 5NT1A; CN-I; CN-IA |
| UniProt Protein Function: | NT5C1A: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia. Belongs to the 5'-nucleotidase type 3 family.Protein type: Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 3.1.3.5; Phosphatase (non-protein)Chromosomal Location of Human Ortholog: 1p34.3-p33Cellular Component: cytosolMolecular Function: 5'-nucleotidase activity; magnesium ion binding; nucleotide bindingBiological Process: adenosine metabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; nucleoside metabolic process; purine base metabolic process; purine nucleoside monophosphate catabolic process; purine nucleotide catabolic process; pyrimidine base metabolic process; pyrimidine nucleoside catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9BXI3 |
| NCBI GenInfo Identifier: | 47116736 |
| NCBI Gene ID: | 84618 |
| NCBI Accession: | Q9BXI3.1 |
| UniProt Secondary Accession: | Q9BXI3,Q3SYB9, Q5TG98, Q9BWT8 |
| UniProt Related Accession: | Q9BXI3 |
| Molecular Weight: | |
| NCBI Full Name: | Cytosolic 5'-nucleotidase 1A |
| NCBI Synonym Full Names: | 5'-nucleotidase, cytosolic IA |
| NCBI Official Symbol: | NT5C1A |
| NCBI Official Synonym Symbols: | CN1; CNI; CN-I; CN1A; CN-IA |
| NCBI Protein Information: | cytosolic 5'-nucleotidase 1A |
| UniProt Protein Name: | Cytosolic 5'-nucleotidase 1A |
| UniProt Synonym Protein Names: | Cytosolic 5'-nucleotidase IA; cN-I; cN-IA |
| Protein Family: | Cytosolic 5'-nucleotidase |
| UniProt Gene Name: | NT5C1A |
| UniProt Entry Name: | 5NT1A_HUMAN |
| Antibodies |
| NT5C1A Antibody (PACO06024) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |

