NT5C1A Antibody (PACO16796)
- SKU:
- PACO16796
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NT5C1A Antibody (PACO16796) |
| Antibody SKU: | PACO16796 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human NT5C1A |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO16796(NT5C1A Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO16796(NT5C1A Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates. Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia. |
| Synonyms: | 5'-nucleotidase, cytosolic IA |
| UniProt Protein Function: | NT5C1A: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia. Belongs to the 5'-nucleotidase type 3 family.Protein type: Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 3.1.3.5; Phosphatase (non-protein)Chromosomal Location of Human Ortholog: 1p34.3-p33Cellular Component: cytosolMolecular Function: 5'-nucleotidase activity; magnesium ion binding; nucleotide bindingBiological Process: adenosine metabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; nucleoside metabolic process; purine base metabolic process; purine nucleoside monophosphate catabolic process; purine nucleotide catabolic process; pyrimidine base metabolic process; pyrimidine nucleoside catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9BXI3 |
| NCBI GenInfo Identifier: | 47116736 |
| NCBI Gene ID: | 84618 |
| NCBI Accession: | Q9BXI3.1 |
| UniProt Secondary Accession: | Q9BXI3,Q3SYB9, Q5TG98, Q9BWT8 |
| UniProt Related Accession: | Q9BXI3 |
| Molecular Weight: | |
| NCBI Full Name: | Cytosolic 5'-nucleotidase 1A |
| NCBI Synonym Full Names: | 5'-nucleotidase, cytosolic IA |
| NCBI Official Symbol: | NT5C1A |
| NCBI Official Synonym Symbols: | CN1; CNI; CN-I; CN1A; CN-IA |
| NCBI Protein Information: | cytosolic 5'-nucleotidase 1A |
| UniProt Protein Name: | Cytosolic 5'-nucleotidase 1A |
| UniProt Synonym Protein Names: | Cytosolic 5'-nucleotidase IA; cN-I; cN-IA |
| Protein Family: | Cytosolic 5'-nucleotidase |
| UniProt Gene Name: | NT5C1A |
| UniProt Entry Name: | 5NT1A_HUMAN |
| Antibodies |
| NT5C1A Antibody (PACO06024) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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