Description
Antibody Name: | Nsf Antibody (PACO33596) |
Antibody SKU: | PACO33596 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Rat |
Immunogen: | Recombinant Rat Vesicle-fusing ATPase protein (7-209AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling. |
Synonyms: | Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF), Nsf, Erg1 |
UniProt Protein Function: | Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling. |
UniProt Protein Details: | |
NCBI Summary: | binds AMPA receptor GluR2 subunit and acts to disrupt GluR2-PICK1 interactions; may play a role in AMPA receptor trafficking and stabilization [RGD, Feb 2006] |
UniProt Code: | Q9QUL6 |
NCBI GenInfo Identifier: | 13489067 |
NCBI Gene ID: | 60355 |
NCBI Accession: | NP_068516.1 |
UniProt Secondary Accession: | Q9QUL6 |
UniProt Related Accession: | Q9QUL6 |
Molecular Weight: | 82,652 Da |
NCBI Full Name: | vesicle-fusing ATPase |
NCBI Synonym Full Names: | N-ethylmaleimide sensitive factor, vesicle fusing ATPase |
NCBI Official Symbol: | Nsf |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | vesicle-fusing ATPase |
UniProt Protein Name: | Vesicle-fusing ATPase |
UniProt Synonym Protein Names: | N-ethylmaleimide-sensitive fusion protein; NEM-sensitive fusion protein; Vesicular-fusion protein NSF |
Protein Family: | |
UniProt Gene Name: | Nsf |
UniProt Entry Name: |