NRXN1 Antibody (PACO10937)
- SKU:
- PACO10937
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NRXN1 Antibody (PACO10937) |
| Antibody SKU: | PACO10937 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human NRXN1 |
| Form: | Liquid |
| Storage Buffer: | 0.1M NaHCO3,0.1M Glycine, 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | neurexin 1;NRXN1;DKFZp313P2036;FLJ35941;Hs.22998;KIAA0578 ; |
| UniProt Protein Function: | Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis. |
| NCBI Summary: | This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia. [provided by RefSeq, Aug 2016] |
| UniProt Code: | Q9ULB1 |
| NCBI GenInfo Identifier: | 1052292378 |
| NCBI Gene ID: | 9378 |
| NCBI Accession: | NP_001317021.1 |
| UniProt Secondary Accession: | Q9ULB1,E7ETA5, |
| UniProt Related Accession: | P58400,Q9ULB1 |
| Molecular Weight: | 161,883 Da |
| NCBI Full Name: | neurexin-1 isoform beta3 |
| NCBI Synonym Full Names: | neurexin 1 |
| NCBI Official Symbol: | NRXN1 |
| NCBI Official Synonym Symbols: | PTHSL2; SCZD17; Hs.22998 |
| NCBI Protein Information: | neurexin-1 |
| UniProt Protein Name: | Neurexin-1-beta |
| UniProt Synonym Protein Names: | Neurexin I-beta |
| Protein Family: | Neurexin |
| UniProt Gene Name: | NRXN1 |
Related Products
