NRL Transcription Factor Activity Assay
- SKU:
- TFAB00208
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- NRL
- Reactivity:
- Human
- Reactivity:
- Mouse
Description
system_update_altDatasheet
| Product Name: | NRL Transcription Factor Activity Assay |
| Product Code: | TFAB00208 |
| Target: | NRL |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie NRL transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B (PubMed:21981118). Functions also as a transcriptional coactivator, stimulating transcription mediated by the transcription factor CRX and NR2E3 (PubMed:17335001). Binds in a sequence-specific manner to the rhodopsin promoter (PubMed:17335001). |
| NCBI Summary: | This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P54845 |
| NCBI GenInfo Identifier: | 5453802 |
| NCBI Gene ID: | 4901 |
| NCBI Accession: | NP_006168.1 |
| UniProt Secondary Accession: | P54845,Q53XD0, A8MX14, |
| UniProt Related Accession: | P54845 |
| Molecular Weight: | 11,276 Da |
| NCBI Full Name: | neural retina-specific leucine zipper protein isoform 1 |
| NCBI Synonym Full Names: | neural retina leucine zipper |
| NCBI Official Symbol: | NRL |
| NCBI Official Synonym Symbols: | RP27; D14S46E; NRL-MAF |
| NCBI Protein Information: | neural retina-specific leucine zipper protein |
| UniProt Protein Name: | Neural retina-specific leucine zipper protein |
| Protein Family: | Neural retina-specific leucine zipper protein |
| UniProt Gene Name: | NRL |
