NRF2 Monoclonal Antibody (CAB3577)
- SKU:
- CAB3577
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | NRF2 Monoclonal Antibody |
| Product Code: | CAB3577 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC0806 |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:100-1:500, IF/ICC 1:50-1:200, IP 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, HeLa |
| Cellular Location: | centrosome, cytoplasm, cytosol, Golgi apparatus, nucleoplasm, nucleus, plasma membrane |
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.
| Immunogen: | A synthesized peptide derived from human NRF2 |
| Sequence: | KNKVA AQNCR KRKLE NIVEL EQDLD HLKDE KEKLL KEKGE NDKSL HLLKK QLSTL YLEVF SMLRD EDGKP YSPSE YSLQQ TRDGN VFLVP KSKKP DVKKN |
| Synonyms: | NRF2, HEBP1, Nrf-2, IMDDHH |
| Calculated MW: | 68kDa |
| Observed MW: | 103kDa |
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