NRF2 Monoclonal Antibody (CAB21176)
- SKU:
- CAB21176
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | NRF2 Monoclonal Antibody |
| Product Code: | CAB21176 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC50393 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, NIH/3T3, C6 |
| Cellular Location: | centrosome, cytoplasm, cytosol, Golgi apparatus, nucleoplasm, nucleus, plasma membrane |
| Customer Validation: | WB(Sus scrofa, Homo sapiens, Mus musculus) IHC(Homo sapiens) Co-IP(Homo sapiens) |
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 243-400 of human NRF2 (NP_006155.2). |
| Sequence: | SPHFL NAFED SFSSI LSTED PNQLT VNSLN SDATV NTDFG DEFYS AFIAE PSISN SMPSP ATLSH SLSEL LNGPI DVSDL SLCKA FNQNH PESTA EFNDS DSGIS LNTSP SVASP EHSVE SSSYG DTLLG LSDSE VEELD SAPGS VKQNG PKTPV HSS |
| Synonyms: | NRF2, HEBP1, Nrf-2, IMDDHH |
| Calculated MW: | 68kDa |
| Observed MW: | 97-100kDa |
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