Description
Antibody Name: | nrdA Antibody (PACO34614) |
Antibody SKU: | PACO34614 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Escherichia coli |
Immunogen: | Recombinant Escherichia coli Ribonucleoside-diphosphate reductase 1 subunit α protein (1-761AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines. |
Synonyms: | Ribonucleoside-diphosphate reductase 1 subunit α (EC 1.17.4.1) (Protein B1) (Ribonucleoside-diphosphate reductase 1 R1 subunit) (Ribonucleotide reductase 1), nrdA, dnaF |
UniProt Protein Function: | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines. |
UniProt Protein Details: | |
NCBI Summary: | Reducing equivalents provided by glutaredoxin or thioredoxin. [More information is available at EcoGene: EG10660]. The B1 protein of ribonucleoside-diphosphate reductase consists of two polypeptide chains of similar or identical size. [More information is available at EcoCyc: EG10660]. |
UniProt Code: | P00452 |
NCBI GenInfo Identifier: | 16130169 |
NCBI Gene ID: | 946612 |
NCBI Accession: | NP_416737.1 |
UniProt Secondary Accession: | P00452,P78088, P78177 |
UniProt Related Accession: | P00452 |
Molecular Weight: | |
NCBI Full Name: | ribonucleoside-diphosphate reductase 1, alpha subunit |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | nrdA |
NCBI Official Synonym Symbols: | dnaF; ECK2226; JW2228 |
NCBI Protein Information: | ribonucleoside-diphosphate reductase 1, alpha subunit |
UniProt Protein Name: | Ribonucleoside-diphosphate reductase 1 subunit alpha |
UniProt Synonym Protein Names: | Protein B1; Ribonucleoside-diphosphate reductase 1 R1 subunit; Ribonucleotide reductase 1 |
Protein Family: | Ribonucleoside-diphosphate reductase |
UniProt Gene Name: | nrdA |
UniProt Entry Name: | RIR1_ECOLI |