NRAS Monoclonal Antibody [PAT2G9AT] (CPAB0444)

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SKU:
CPAB0444
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT2G9AT
Applications:
WB
Applications:
ELISA

Description

system_update_alt Datasheet
Product Name:NRAS Antibody
Product Sku:CPAB0444
Size:5μg
Host Species:Mouse
Immunogen:Anti-human NRAS mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NRAS amino acids 1-186 purified from Ecoli.
Clone:PAT2G9AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:NRAS antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2a
Background:NRAS binds GDP/GTP and has intrinsic GTPase activity. NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This transport is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. NRAS is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in this NRAS gene result in juvenile myelomonocytic leukemia.
Synonyms:GTPase NRas, HRAS1, ALPS4, N-ras, NRAS1, NS6, Transforming protein N-Ras.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
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