Description
Antibody Name: | Nqo2 Antibody (PACO36434) |
Antibody SKU: | PACO36434 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
Species Reactivity: | Rat, Mouse |
Immunogen: | Recombinant Rat Ribosyldihydronicotinamide dehydrogenase [quinone] protein (1-231AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: Nqo2 antibody at 8µg/ml. Lane 1: Rat heart tissue. Lane 2: Mouse liver tissue. Lane 3: Mouse kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 27 kDa. Observed band size: 27 kDa. |
Background: | The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. |
Synonyms: | Ribosyldihydronicotinamide dehydrogenase [quinone] (EC 1.10.5.1) (NRH dehydrogenase [quinone] 2) (NRH:quinone oxidoreductase 2) (Quinone reductase 2) (QR2), Nqo2 |
UniProt Protein Function: | The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. |
UniProt Protein Details: | |
NCBI Summary: | mouse homolog catalyzes the reduction of quinones and quinone derivatives; may protect against development of myelogenous hyperplasia , may contribute to menadione mediated hepatic toxicity [RGD, Feb 2006] |
UniProt Code: | Q6AY80 |
NCBI GenInfo Identifier: | 51948400 |
NCBI Gene ID: | 291084 |
NCBI Accession: | NP_001004214.1 |
UniProt Secondary Accession: | Q6AY80 |
UniProt Related Accession: | Q6AY80 |
Molecular Weight: | 26,275 Da |
NCBI Full Name: | ribosyldihydronicotinamide dehydrogenase |
NCBI Synonym Full Names: | N-ribosyldihydronicotinamide:quinone reductase 2 |
NCBI Official Symbol: | Nqo2 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | ribosyldihydronicotinamide dehydrogenase [quinone] |
UniProt Protein Name: | Ribosyldihydronicotinamide dehydrogenase [quinone] |
UniProt Synonym Protein Names: | NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; Quinone reductase 2; QR2 |
Protein Family: | Ribosyldihydronicotinamide dehydrogenase |
UniProt Gene Name: | Nqo2 |
UniProt Entry Name: |