Description
Antibody Name: | NPTX1 Antibody (PACO55102) |
Antibody SKU: | PACO55102 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Neuronal pentraxin-1 protein (88-227AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human breast cancer using PACO55102 at dilution of 1:100. |
![]() | Immunofluorescent analysis of Hela cells using PACO55102 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. |
Synonyms: | Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I), NPTX1 |
UniProt Protein Function: | NPTX1: May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 17q25.3 Biological Process: central nervous system development; synaptic transmission; transport |
NCBI Summary: | NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q15818 |
NCBI GenInfo Identifier: | 77416871 |
NCBI Gene ID: | 4884 |
NCBI Accession: | Q15818.2 |
UniProt Secondary Accession: | Q15818,Q5FWE6, B3KXH3, |
UniProt Related Accession: | Q15818 |
Molecular Weight: | 47,122 Da |
NCBI Full Name: | Neuronal pentraxin-1 |
NCBI Synonym Full Names: | neuronal pentraxin 1 |
NCBI Official Symbol: | NPTX1 |
NCBI Official Synonym Symbols: | NP1 |
NCBI Protein Information: | neuronal pentraxin-1 |
UniProt Protein Name: | Neuronal pentraxin-1 |
UniProt Synonym Protein Names: | Neuronal pentraxin I; NP-I |
Protein Family: | Neuronal pentraxin |
UniProt Gene Name: | NPTX1 |
UniProt Entry Name: | NPTX1_HUMAN |
Antibodies |
NPTX1 Antibody (PACO10912) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |