NPM2 Antibody (PACO37458)
- SKU:
- PACO37458
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NPM2 Antibody (PACO37458) |
| Antibody SKU: | PACO37458 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Nucleoplasmin-2 protein (1-136AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO37458 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO37458 at dilution of 1:100. |
| Background: | Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization. |
| Synonyms: | Nucleoplasmin-2, NPM2 |
| UniProt Protein Function: | NPM2: Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization. Belongs to the nucleoplasmin family.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 8p21.3Cellular Component: nuclear chromatin; nucleusMolecular Function: enzyme binding; nucleic acid binding; histone binding; chromatin bindingBiological Process: chromatin remodeling; positive regulation of catalytic activity; embryonic development; positive regulation of meiosis; single fertilization; regulation of exit from mitosis; oocyte differentiation; protein homooligomerization; positive regulation of DNA replication |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q86SE8 |
| NCBI GenInfo Identifier: | 37537936 |
| NCBI Gene ID: | 10361 |
| NCBI Accession: | Q86SE8.1 |
| UniProt Secondary Accession: | Q86SE8,Q6NVH6, B3KSU0, D3DSQ8 |
| UniProt Related Accession: | Q86SE8 |
| Molecular Weight: | 15,238 Da |
| NCBI Full Name: | Nucleoplasmin-2 |
| NCBI Synonym Full Names: | nucleophosmin/nucleoplasmin 2 |
| NCBI Official Symbol: | NPM2 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | nucleoplasmin-2 |
| UniProt Protein Name: | Nucleoplasmin-2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Nucleoplasmin |
| UniProt Gene Name: | NPM2 |
| UniProt Entry Name: | NPM2_HUMAN |
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