Description
system_update_alt Datasheet
Product Name: | NPM1 Antibody |
Product Sku: | CPAB0631 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human NPM1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NPM1 protein 1-294 amino acids purified from Ecoli. |
Clone: | PAT23F1AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA, Flow Cytometry |
Purification Method: | NPM1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2b |
Background: | Nucleophosmin (NPM1) is a phosphoprotein which shuffles between the nucleus and the cytoplasm. NPM1 is assumed to be involved in a number of processes including regulation of the ARF/p53 pathway. Several genes fusion partners have been described, particularly the anaplastic lymphoma kinase gene on chromosome 2. NPM1 gene mutations are linked with acute myeloid leukemia. |
Synonyms: | Nucleophosmin, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, NPM1, NPM, B23. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |