NPBWR2 Antibody (PACO28606)
- SKU:
- PACO28606
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NPBWR2 Antibody (PACO28606) |
| Antibody SKU: | PACO28606 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Neuropeptides B/W receptor type 2 protein (1-45AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of A549 cells using PACO28606 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. |
| Synonyms: | Neuropeptides B/W receptor type 2 (G-protein coupled receptor 8), NPBWR2, GPR8 |
| UniProt Protein Function: | NPBWR2: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCRChromosomal Location of Human Ortholog: 20q13.3Cellular Component: integral to membrane; integral to plasma membrane; neuron projection; plasma membraneMolecular Function: neuropeptide binding; neuropeptide receptor activity; opioid receptor activity; protein bindingBiological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; neuropeptide signaling pathway; synaptic transmission |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor. The encoded protein is similar in sequence to another G protein-coupled receptor (GPR7), and it is structurally similar to opioid and somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P48146 |
| NCBI GenInfo Identifier: | 160332190 |
| NCBI Gene ID: | 2832 |
| NCBI Accession: | P48146.2 |
| UniProt Secondary Accession: | P48146,Q6NWQ6, Q9H4K3 |
| UniProt Related Accession: | P48146 |
| Molecular Weight: | 36,861 Da |
| NCBI Full Name: | Neuropeptides B/W receptor type 2 |
| NCBI Synonym Full Names: | neuropeptides B/W receptor 2 |
| NCBI Official Symbol: | NPBWR2 |
| NCBI Official Synonym Symbols: | GPR8 |
| NCBI Protein Information: | neuropeptides B/W receptor type 2 |
| UniProt Protein Name: | Neuropeptides B/W receptor type 2 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 8 |
| Protein Family: | |
| UniProt Gene Name: | NPBWR2 |
| UniProt Entry Name: | NPBW2_HUMAN |
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