NPAS4 Antibody (PACO22467)
- SKU:
- PACO22467
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NPAS4 Antibody (PACO22467) |
| Antibody SKU: | PACO22467 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human NPAS4. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry analysis of paraffin-embedded human brain tissue using NPAS4 antibody. |
| Background: | Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene. |
| Synonyms: | Neuronal PAS domain-containing protein 4; Neuronal PAS4; HLH-PAS transcription factor NXF; |
| UniProt Protein Function: | NPAS4: Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 11q13Cellular Component: transcription factor complex; nucleusMolecular Function: signal transducer activity; protein heterodimerization activityBiological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8IUM7 |
| NCBI GenInfo Identifier: | 194097477 |
| NCBI Gene ID: | 266743 |
| NCBI Accession: | NP_849195.2 |
| UniProt Secondary Accession: | Q8IUM7,Q8N8S5, Q8N9Q9, B7ZL81 |
| UniProt Related Accession: | Q8IUM7 |
| Molecular Weight: | |
| NCBI Full Name: | neuronal PAS domain-containing protein 4 |
| NCBI Synonym Full Names: | neuronal PAS domain protein 4 |
| NCBI Official Symbol: | NPAS4 |
| NCBI Official Synonym Symbols: | NXF; Le-PAS; PASD10; bHLHe79 |
| NCBI Protein Information: | neuronal PAS domain-containing protein 4 |
| UniProt Protein Name: | Neuronal PAS domain-containing protein 4 |
| UniProt Synonym Protein Names: | Class E basic helix-loop-helix protein 79; bHLHe79; HLH-PAS transcription factor NXF; PAS domain-containing protein 10 |
| Protein Family: | Neuronal PAS domain-containing protein |
| UniProt Gene Name: | NPAS4 |
| UniProt Entry Name: | NPAS4_HUMAN |
| Antibodies |
| NPAS4 Antibody (PACO03852) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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