NPAS4 Antibody (PACO03852)
- SKU:
- PACO03852
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NPAS4 Antibody |
| Antibody SKU: | PACO03852 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the C-terminal region of human NPAS4. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | NPAS4; BHLHE79; NXF; PASD10; Neuronal PAS domain-containing protein 4; Neuronal PAS4; Class E basic helix-loop-helix protein 79; bHLHe79; HLH-PAS transcription factor NXF; PAS domain-containing protein 10 |
| UniProt Protein Function: | NPAS4: Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 11q13Cellular Component: transcription factor complex; nucleusMolecular Function: signal transducer activity; protein heterodimerization activityBiological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8IUM7 |
| NCBI GenInfo Identifier: | 194097477 |
| NCBI Gene ID: | 266743 |
| NCBI Accession: | NP_849195.2 |
| UniProt Secondary Accession: | Q8IUM7,Q8N8S5, Q8N9Q9, B7ZL81 |
| UniProt Related Accession: | Q8IUM7 |
| Molecular Weight: | |
| NCBI Full Name: | neuronal PAS domain-containing protein 4 |
| NCBI Synonym Full Names: | neuronal PAS domain protein 4 |
| NCBI Official Symbol: | NPAS4 |
| NCBI Official Synonym Symbols: | NXF; Le-PAS; PASD10; bHLHe79 |
| NCBI Protein Information: | neuronal PAS domain-containing protein 4 |
| UniProt Protein Name: | Neuronal PAS domain-containing protein 4 |
| UniProt Synonym Protein Names: | Class E basic helix-loop-helix protein 79; bHLHe79; HLH-PAS transcription factor NXF; PAS domain-containing protein 10 |
| Protein Family: | Neuronal PAS domain-containing protein |
| UniProt Gene Name: | NPAS4 |
| UniProt Entry Name: | NPAS4_HUMAN |
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