NOM1 Antibody (PACO05039)
- SKU:
- PACO05039
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NOM1 Antibody (PACO05039) |
| Antibody SKU: | PACO05039 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:40000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human NOM1. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | NOM1; C7orf3; Nucleolar MIF4G domain-containing protein 1; SGD1 homolog |
| UniProt Protein Function: | NOM1: a nucleolar protein that binds eIF4A and encoded within the chromosome 7q36 breakpoint region associated with pediatric acute myeloid leukemia. Contains an MIF4G and an MA3 domain. MIF4G and MA3 domains bind proteins of the eIF4A family of ATP-dependent DEAD-box RNA helicases required for both translation and nonsense-mediated decay. MIF4G domains are found in several proteins involved in RNA metabolism, including eIF4G, eIF-2b, UPF2, and nuclear cap-binding proteins.Protein type: Nucleolus; Unknown functionChromosomal Location of Human Ortholog: 7q36.3Cellular Component: nucleolus; nucleusMolecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 [PubMed 15715967]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q5C9Z4 |
| NCBI GenInfo Identifier: | 61097912 |
| NCBI Gene ID: | 64434 |
| NCBI Accession: | NP_612409.1 |
| UniProt Secondary Accession: | Q5C9Z4,Q96I08 |
| UniProt Related Accession: | Q5C9Z4 |
| Molecular Weight: | 96,257 Da |
| NCBI Full Name: | nucleolar MIF4G domain-containing protein 1 |
| NCBI Synonym Full Names: | nucleolar protein with MIF4G domain 1 |
| NCBI Official Symbol: | NOM1 |
| NCBI Official Synonym Symbols: | SGD1; C7orf3; PPP1R113 |
| NCBI Protein Information: | nucleolar MIF4G domain-containing protein 1; SGD1 homolog; protein phosphatase 1, regulatory subunit 113 |
| UniProt Protein Name: | Nucleolar MIF4G domain-containing protein 1 |
| UniProt Synonym Protein Names: | SGD1 homolog |
| Protein Family: | Nucleolar MIF4G domain-containing protein |
| UniProt Gene Name: | NOM1 |
| UniProt Entry Name: | NOM1_HUMAN |
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