Description
| Antibody Name: | NOL8 Antibody (PACO10890) |
| Antibody SKU: | PACO10890 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human NOL8 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | nucleolar protein 8;NOL8;C9orf34;DKFZp686P12242;FLJ20736;Nop132;bA62C3.3;bA62C3.4 ; |
| UniProt Protein Function: | NOL8: Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Nucleolus; RNA-bindingChromosomal Location of Human Ortholog: 9q22.31Cellular Component: cytoplasm; nucleolus; nucleusMolecular Function: nucleotide binding; protein bindingBiological Process: DNA replication; positive regulation of cell growth; rRNA processing |
| UniProt Protein Details: | |
| NCBI Summary: | NOL8 binds Ras-related GTP-binding proteins (see MIM 608267) and plays a role in cell growth (Sekiguchi et al., 2004 [PubMed 14660641]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q76FK4 |
| NCBI GenInfo Identifier: | 74758950 |
| NCBI Gene ID: | 55035 |
| NCBI Accession: | Q76FK4.1 |
| UniProt Secondary Accession: | Q76FK4,Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7 Q76D35, Q7L3E2, Q9H586 |
| UniProt Related Accession: | Q76FK4 |
| Molecular Weight: | 127,337 Da |
| NCBI Full Name: | Nucleolar protein 8 |
| NCBI Synonym Full Names: | nucleolar protein 8 |
| NCBI Official Symbol: | NOL8 |
| NCBI Official Synonym Symbols: | NOP132; C9orf34; bA62C3.3; bA62C3.4 |
| NCBI Protein Information: | nucleolar protein 8 |
| UniProt Protein Name: | Nucleolar protein 8 |
| UniProt Synonym Protein Names: | Nucleolar protein Nop132 |
| Protein Family: | Nucleolar protein |
| UniProt Gene Name: | NOL8 |
| UniProt Entry Name: | NOL8_HUMAN |