Description
Product Name: | Nogo Monoclonal Antibody |
Product Code: | CAB2315 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC1910 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:100-1:500, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | SH-SY5Y |
Cellular Location: | Endoplasmic reticulum, Glutamatergic synapse, Neuron projection, Nuclear envelope, Plasma membrane, Postsynaptic density |
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.
Immunogen: | A synthesized peptide derived from human Nogo |
Sequence: | Email for sequence |
Synonyms: | ASY, NSP, NOGO, RTN-X, NSP-CL, RTN4-A, RTN4-C, RTN4-B1, RTN4-B2, NI220/250, Nbla00271, Nbla10545 |
Calculated MW: | 130kDa |
Observed MW: | 45kDa |