NNMT Monoclonal Antibody [PAT11G11AT] (CPAB0219)
![NNMT Monoclonal Antibody [PAT11G11AT] (CPAB0219)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58445/63627/nnmt-monoclonal-antibody-pat11g11at-cpab0219__71881__24871.1706535014.jpg?c=1 "NNMT Monoclonal Antibody [PAT11G11AT] (CPAB0219)")
- SKU:
- CPAB0219
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT11G11AT
- Applications:
- ELISA
- Applications:
- FC
![NNMT Monoclonal Antibody [PAT11G11AT] (CPAB0219)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58445/63627/nnmt-monoclonal-antibody-pat11g11at-cpab0219__71881__24871.1706535014.jpg?c=1&imbypass=on "NNMT Monoclonal Antibody [PAT11G11AT] (CPAB0219)")
Description
system_update_alt Datasheet
| Product Name: | NNMT Antibody |
| Product Sku: | CPAB0219 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human NNMT mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NNMT protein 1-264 amino acids purified from Ecoli. |
| Clone: | PAT11G11AT. |
| Reactivity: | Human |
| Applications: | ELISA, Flow Cytometry |
| Purification Method: | NNMT antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG2a |
| Background: | NNMT is part of the family of transferases, especially those transferring one-carbon group methyltransferases. NNMT is mostly expressed in the liver, and a lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. NNMT catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is significant for biotransformation of many drugs and xenobiotic compounds. NNMT is accountable for the enzymatic activity which uses S-adenosyl methionine as the methyl donor. NNMT expression is related with tumor stage and DFS time in hepatocellular carcinoma cases. NNMT is a good candidate as a tumor marker of various kinds of cancers. NNMT serum levels have significance in the premature detection and in the management of patients with colorectal cancer. |
| Synonyms: | Nicotineamide N-methyltransferase. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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