NMBR Antibody (PACO55686)
- SKU:
- PACO55686
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NMBR Antibody (PACO55686) |
| Antibody SKU: | PACO55686 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Neuromedin-B receptor protein (1-41AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate. All lanes: NMBR antibody at 4.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 44 kDa. Observed band size: 44 kDa. |
| Background: | Receptor for neuromedin-B. |
| Synonyms: | Neuromedin-B receptor (NMB-R) (Epididymis tissue protein Li 185a) (Neuromedin-B-preferring bombesin receptor), NMBR |
| UniProt Protein Function: | NMBR: Receptor for neuromedin-B. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integralChromosomal Location of Human Ortholog: 6q24.1Cellular Component: cytoplasm; integral to plasma membrane; plasma membraneBiological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016] |
| UniProt Code: | P28336 |
| NCBI GenInfo Identifier: | 212286370 |
| NCBI Gene ID: | 4829 |
| NCBI Accession: | P28336.2 |
| UniProt Secondary Accession: | P28336,Q5VUK8, E9KL38 |
| UniProt Related Accession: | P28336, AAB27330 |
| Molecular Weight: | 43,435 Da |
| NCBI Full Name: | Neuromedin-B receptor |
| NCBI Synonym Full Names: | neuromedin B receptor |
| NCBI Official Symbol: | NMBR |
| NCBI Official Synonym Symbols: | BB1; BB1R; NMB-R |
| NCBI Protein Information: | neuromedin-B receptor |
| UniProt Protein Name: | Neuromedin-B receptor |
| UniProt Synonym Protein Names: | Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor |
| Protein Family: | Neuromedin-B receptor |
| UniProt Gene Name: | NMBR |
| UniProt Entry Name: | NMBR_HUMAN |
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