Description
Antibody Name: | NMBR Antibody (PACO55686) |
Antibody SKU: | PACO55686 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Neuromedin-B receptor protein (1-41AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate. All lanes: NMBR antibody at 4.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 44 kDa. Observed band size: 44 kDa. |
Background: | Receptor for neuromedin-B. |
Synonyms: | Neuromedin-B receptor (NMB-R) (Epididymis tissue protein Li 185a) (Neuromedin-B-preferring bombesin receptor), NMBR |
UniProt Protein Function: | NMBR: Receptor for neuromedin-B. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integralChromosomal Location of Human Ortholog: 6q24.1Cellular Component: cytoplasm; integral to plasma membrane; plasma membraneBiological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016] |
UniProt Code: | P28336 |
NCBI GenInfo Identifier: | 212286370 |
NCBI Gene ID: | 4829 |
NCBI Accession: | P28336.2 |
UniProt Secondary Accession: | P28336,Q5VUK8, E9KL38 |
UniProt Related Accession: | P28336, AAB27330 |
Molecular Weight: | 43,435 Da |
NCBI Full Name: | Neuromedin-B receptor |
NCBI Synonym Full Names: | neuromedin B receptor |
NCBI Official Symbol: | NMBR |
NCBI Official Synonym Symbols: | BB1; BB1R; NMB-R |
NCBI Protein Information: | neuromedin-B receptor |
UniProt Protein Name: | Neuromedin-B receptor |
UniProt Synonym Protein Names: | Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor |
Protein Family: | Neuromedin-B receptor |
UniProt Gene Name: | NMBR |
UniProt Entry Name: | NMBR_HUMAN |