NMBR Antibody (PACO02932)
- SKU:
- PACO02932
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NMBR Antibody |
| Antibody SKU: | PACO02932 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human NMBR. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | NMBR; Neuromedin-B receptor; NMB-R; Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor |
| UniProt Protein Function: | NMBR: Receptor for neuromedin-B. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integralChromosomal Location of Human Ortholog: 6q24.1Cellular Component: cytoplasm; integral to plasma membrane; plasma membraneBiological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016] |
| UniProt Code: | P28336 |
| NCBI GenInfo Identifier: | 212286370 |
| NCBI Gene ID: | 4829 |
| NCBI Accession: | P28336.2 |
| UniProt Secondary Accession: | P28336,Q5VUK8, E9KL38 |
| UniProt Related Accession: | P28336, AAB27330 |
| Molecular Weight: | 43,435 Da |
| NCBI Full Name: | Neuromedin-B receptor |
| NCBI Synonym Full Names: | neuromedin B receptor |
| NCBI Official Symbol: | NMBR |
| NCBI Official Synonym Symbols: | BB1; BB1R; NMB-R |
| NCBI Protein Information: | neuromedin-B receptor |
| UniProt Protein Name: | Neuromedin-B receptor |
| UniProt Synonym Protein Names: | Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor |
| Protein Family: | Neuromedin-B receptor |
| UniProt Gene Name: | NMBR |
| UniProt Entry Name: | NMBR_HUMAN |
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