NLRP9 Antibody (PACO20106)
- SKU:
- PACO20106
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NLRP9 Antibody (PACO20106) |
| Antibody SKU: | PACO20106 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human NLRP9 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO20106(NLRP9 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. |
| Synonyms: | NLR family, pyrin domain containing 9 |
| UniProt Protein Function: | NLRP9: Involved in inflammation (Potential). Belongs to the NLRP family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 19q13.42Cellular Component: cytoplasmMolecular Function: ATP binding |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q7RTR0 |
| NCBI GenInfo Identifier: | 74762418 |
| NCBI Gene ID: | 338321 |
| NCBI Accession: | Q7RTR0.1 |
| UniProt Secondary Accession: | Q7RTR0,Q86W27, B2RN12 |
| UniProt Related Accession: | Q7RTR0 |
| Molecular Weight: | 112,593 Da |
| NCBI Full Name: | NACHT, LRR and PYD domains-containing protein 9 |
| NCBI Synonym Full Names: | NLR family, pyrin domain containing 9 |
| NCBI Official Symbol: | NLRP9 |
| NCBI Official Synonym Symbols: | NOD6; NALP9; PAN12; CLR19.1 |
| NCBI Protein Information: | NACHT, LRR and PYD domains-containing protein 9; PYRIN and NACHT-containing protein 12; NACHT, LRR and PYD containing protein 9; NACHT, leucine rich repeat and PYD containing 9; nucleotide-binding oligomerization domain protein 6; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 9 |
| UniProt Protein Name: | NACHT, LRR and PYD domains-containing protein 9 |
| UniProt Synonym Protein Names: | Nucleotide-binding oligomerization domain protein 6; PYRIN and NACHT-containing protein 12 |
| Protein Family: | NACHT, LRR and PYD domains-containing protein |
| UniProt Gene Name: | NLRP9 |
| UniProt Entry Name: | NALP9_HUMAN |
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