Description
Product Name: | Nlrp6 Polyclonal Antibody |
Product Code: | CAB23267 |
Reactivity: | Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Positive Samples: | Rat colon |
The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 124-237 of mouse Nlrp6(NP_598707.2 ). |
Sequence: | RQHAK VKERN ARSVK INKRF TKLLI APGTG AVEDE LLGPL GEPEP ERARR SDTHT FNRLF RGNDE ESSQP LTVVL QGPAG IGKTM AAKKI LYDWA AGKLY HSQVD FAFFM PCGE |
Synonyms: | Avr, Navr, Nalp6, Pypaf5, Non-AVR, Navr/Avr |
Calculated MW: | 97kDa |
Observed MW: | 101kDa |