Name: NIT2 Antibody (PACO41682)
SKU: PACO41682
Availability: OutOfStock

Antibody Name:	NIT2 Antibody (PACO41682)
Antibody SKU:	PACO41682
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:	Human, Mouse
Immunogen:	Recombinant Human Omega-amidase NIT2 protein (1-276AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Western blot. All lanes: NIT2 antibody at 3µg/ml. Lane 1: Mouse heart tissue. Lane 2: A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 31 kDa. Observed band size: 31 kDa.

Background:	Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.
Synonyms:	Omega-amidase NIT2 (EC 3.5.1.3) (Nitrilase homolog 2), NIT2

UniProt Protein Function:	NIT2: a protein of unknown function. A CN hydrolase domain suggests that this protein may be involved in nitrilase-related metabolism and handling.
UniProt Protein Details:	Protein type:EC 3.5.1.3; Hydrolase; Mitochondrial Chromosomal Location of Human Ortholog: 3q12.2 Cellular Component: centrosome; mitochondrion; cytoplasm Molecular Function:omega-amidase activity Biological Process: oxaloacetate metabolic process; glutamine metabolic process; asparagine metabolic process
UniProt Code:	Q9NQR4
NCBI GenInfo Identifier:	74725271
NCBI Gene ID:	56954
NCBI Accession:	Q9NQR4.1
UniProt Secondary Accession:	Q9NQR4,Q8WUF0, B2R9A3, D3DN47,
UniProt Related Accession:	Q9NQR4
Molecular Weight:	276
NCBI Full Name:	Omega-amidase NIT2
NCBI Synonym Full Names:	nitrilase family, member 2
NCBI Official Symbol:	NIT2
NCBI Official Synonym Symbols:	HEL-S-8a
NCBI Protein Information:	omega-amidase NIT2; Nit protein 2; nitrilase homolog 2; epididymis secretory sperm binding protein Li 8a
UniProt Protein Name:	Omega-amidase NIT2
UniProt Synonym Protein Names:	Nitrilase homolog 2
Protein Family:	Nitrilase
UniProt Gene Name:	NIT2
UniProt Entry Name:	NIT2_HUMAN