NIT2 Antibody (PACO18757)
- SKU:
- PACO18757
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NIT2 Antibody (PACO18757) |
| Antibody SKU: | PACO18757 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human NIT2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18757(NIT2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse liver tissue, Mouse kidney tissue, RAW264.7 cells, Primary antibody: PACO18757(NIT2 Antibody) at dilution 1/950, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 90 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18757(NIT2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle. |
| Synonyms: | Itrilase family, member 2 |
| UniProt Protein Function: | NIT2: a protein of unknown function. A CN hydrolase domain suggests that this protein may be involved in nitrilase-related metabolism and handling. |
| UniProt Protein Details: | Protein type:EC 3.5.1.3; Hydrolase; Mitochondrial Chromosomal Location of Human Ortholog: 3q12.2 Cellular Component: centrosome; mitochondrion; cytoplasm Molecular Function:omega-amidase activity Biological Process: oxaloacetate metabolic process; glutamine metabolic process; asparagine metabolic process |
| UniProt Code: | Q9NQR4 |
| NCBI GenInfo Identifier: | 74725271 |
| NCBI Gene ID: | 56954 |
| NCBI Accession: | Q9NQR4.1 |
| UniProt Secondary Accession: | Q9NQR4,Q8WUF0, B2R9A3, D3DN47, |
| UniProt Related Accession: | Q9NQR4 |
| Molecular Weight: | 276 |
| NCBI Full Name: | Omega-amidase NIT2 |
| NCBI Synonym Full Names: | nitrilase family, member 2 |
| NCBI Official Symbol: | NIT2 |
| NCBI Official Synonym Symbols: | HEL-S-8a |
| NCBI Protein Information: | omega-amidase NIT2; Nit protein 2; nitrilase homolog 2; epididymis secretory sperm binding protein Li 8a |
| UniProt Protein Name: | Omega-amidase NIT2 |
| UniProt Synonym Protein Names: | Nitrilase homolog 2 |
| Protein Family: | Nitrilase |
| UniProt Gene Name: | NIT2 |
| UniProt Entry Name: | NIT2_HUMAN |
| Antibodies |
| NIT2 Antibody (PACO10860) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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