Description
Antibody Name: | NHLH1/NHLH2 Antibody (PACO21822) |
Antibody SKU: | PACO21822 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from internal of human HEN1/2. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen The MGC Project Team, Genome Res. 14:2121-2127(2004). |
Clonality: | Polyclonal |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from Jurkat cells, using HEN1/2 antibody. |
Synonyms: | Helix-loop-helix protein 1; HEN1; Nescient helix loop helix 1; NSCL-1; NHLH1 |
UniProt Protein Function: | NHLH1: May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q22 Cellular Component: nucleus Biological Process: central nervous system development; positive regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM, Nov 2002] |
UniProt Code: | Q02575 |
NCBI GenInfo Identifier: | 399885 |
NCBI Gene ID: | 4807 |
NCBI Accession: | Q02575.1 |
UniProt Related Accession: | Q02575 |
Molecular Weight: | 14,618 Da |
NCBI Full Name: | Helix-loop-helix protein 1 |
NCBI Synonym Full Names: | nescient helix-loop-helix 1 |
NCBI Official Symbol: | NHLH1 |
NCBI Official Synonym Symbols: | HEN1; NSCL; NSCL1; bHLHa35 |
NCBI Protein Information: | helix-loop-helix protein 1 |
UniProt Protein Name: | Helix-loop-helix protein 1 |
UniProt Synonym Protein Names: | Class A basic helix-loop-helix protein 35; bHLHa35; Nescient helix loop helix 1; NSCL-1 |
Protein Family: | Helix-loop-helix protein |
UniProt Gene Name: | NHLH1 |
UniProt Entry Name: | HEN1_HUMAN |
Antibodies |
NHLH1/NHLH2 Antibody (PACO00903) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |