NHLH1/NHLH2 Antibody (PACO00903)
- SKU:
- PACO00903
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NHLH1/NHLH2 Antibody |
| Antibody SKU: | PACO00903 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | synthesized peptide derived from the Internal region of human HEN1/2. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | NHLH1; BHLHA35; HEN1; Helix-loop-helix protein 1; HEN-1; Class A basic helix-loop-helix protein 35; bHLHa35; Nescient helix loop helix 1; NSCL-1; NHLH2; BHLHA34; HEN2; KIAA0490; Helix-loop-helix protein 2; HEN-2; Class A basic helix-loop-he |
| UniProt Protein Function: | NHLH1: May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q22 Cellular Component: nucleus Biological Process: central nervous system development; positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM, Nov 2002] |
| UniProt Code: | Q02575 |
| NCBI GenInfo Identifier: | 399885 |
| NCBI Gene ID: | 4807 |
| NCBI Accession: | Q02575.1 |
| UniProt Related Accession: | Q02575 |
| Molecular Weight: | 14,618 Da |
| NCBI Full Name: | Helix-loop-helix protein 1 |
| NCBI Synonym Full Names: | nescient helix-loop-helix 1 |
| NCBI Official Symbol: | NHLH1 |
| NCBI Official Synonym Symbols: | HEN1; NSCL; NSCL1; bHLHa35 |
| NCBI Protein Information: | helix-loop-helix protein 1 |
| UniProt Protein Name: | Helix-loop-helix protein 1 |
| UniProt Synonym Protein Names: | Class A basic helix-loop-helix protein 35; bHLHa35; Nescient helix loop helix 1; NSCL-1 |
| Protein Family: | Helix-loop-helix protein |
| UniProt Gene Name: | NHLH1 |
| UniProt Entry Name: | HEN1_HUMAN |
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