Description
| Product Name: | NHLH1 Monoclonal Antibody |
| Product Code: | CAB24828 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC64632 |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T transfected with NHLH1 (Human) |
| Cellular Location: | Nucleus |
The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human NHLH1 (NP_005589.1). |
| Sequence: | MMLNS DTMEL DLPPT HSETE SGFSD CGGGA GPDGA GPGGP GGGQA RGPEP GEPGR KDLQH |
| Synonyms: | HEN1, NSCL, NSCL1, bHLHa35 |
| Calculated MW: | 15kDa |
| Observed MW: | 22kDa |