Description
Product Name: | NHEJ1 Polyclonal Antibody |
Product Code: | CAB21661 |
Reactivity: | Human, Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | Nucleus |
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human NHEJ1 (NP_079058.1). |
Sequence: | MEELE QGLLM QPWAW LQLAE NSLLA KVFIT KQGYA LLVSD LQQVW HEQVD TSVVS QRAKE LNKRL TAPPA AFLCH LDNLL RPLLK DAAHP SEATF SCDCV ADALI LRVRS ELSGL PFYWN FHCML ASPSL VSQHL IRPLM GMSLA LQCQV RELAT LLHMK DLEIQ DYQES GATLI RDRLK TEPFE ENSFL EQFMI EKLPE ACSIG DGKPF VMNLQ DLYMA VTTQE VQVGQ KHQGA GDPHT SNSAS LQGID SQCVN QPEQL VSSAP TLSAP EKEST GTSGP LQRPQ LSKVK RKKPR GLFS |
Synonyms: | XLF |
Calculated MW: | 33kDa |
Observed MW: | Refer to figures |