Description
| Product Name: | NG2/CSPG4 Polyclonal Antibody |
| Product Code: | CAB22556 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | A375, Mouse lung |
| Cellular Location: | apical plasma membrane, cell projection, cell surface, lamellipodium membrane, nucleoplasm, plasma membrane |
Enables coreceptor activity. Acts upstream of or within several processes, including platelet-derived growth factor receptor signaling pathway; positive regulation of MAPK cascade; and ruffle assembly. Located in plasma membrane and ruffle. Is expressed in several structures, including brain; jaw; respiratory system; retina; and skeleton. Human ortholog(s) of this gene implicated in relapsing-remitting multiple sclerosis. Orthologous to human CSPG4 (chondroitin sulfate proteoglycan 4).
| Immunogen: | Recombinant protein of human NG2/CSPG4. |
| Sequence: | Email for sequence |
| Synonyms: | AN2, NG2, Cspg4a, 4732461B14Rik |
| Calculated MW: | 252kDa |
| Observed MW: | 270-300kDa |