Description
Product Name: | NG2/CSPG4 Polyclonal Antibody |
Product Code: | CAB22556 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | A375, Mouse lung |
Cellular Location: | apical plasma membrane, cell projection, cell surface, lamellipodium membrane, nucleoplasm, plasma membrane |
Enables coreceptor activity. Acts upstream of or within several processes, including platelet-derived growth factor receptor signaling pathway; positive regulation of MAPK cascade; and ruffle assembly. Located in plasma membrane and ruffle. Is expressed in several structures, including brain; jaw; respiratory system; retina; and skeleton. Human ortholog(s) of this gene implicated in relapsing-remitting multiple sclerosis. Orthologous to human CSPG4 (chondroitin sulfate proteoglycan 4).
Immunogen: | Recombinant protein of human NG2/CSPG4. |
Sequence: | Email for sequence |
Synonyms: | AN2, NG2, Cspg4a, 4732461B14Rik |
Calculated MW: | 252kDa |
Observed MW: | 270-300kDa |