Description
Product Name: | NG2/CSPG4 Polyclonal Antibody |
Product Code: | CAB22012 |
Reactivity: | Human, Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, MCF7, Mouse heart |
Cellular Location: | apical plasma membrane, cell surface, extracellular exosome, extracellular region, focal adhesion, Golgi lumen, lamellipodium membrane, lysosomal lumen, nucleoplasm, plasma membrane |
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1340-1563 of human NG2/CSPG4 (NP_001888.2). |
Sequence: | LGAPL EGVLV ELEVL PAAIP LEAQN FSVPE GGSLT LAPPL LRVSG PYFPT LLGLS LQVLE PPQHG ALQKE DGPQA RTLSA FSWRM VEEQL IRYVH DGSET LTDSF VLMAN ASEMD RQSHP VAFTV TVLPV NDQPP ILTTN TGLQM WEGAT APIPA EALRS TDGDS GSEDL VYTIE QPSNG RVVLR GAPGT EVRSF TQAQL DGGLV LFSHR GTLDG GFRFR LSDG |
Synonyms: | NG2, MCSP, MCSPG, MSK16, CSPG4A, HMW-MAA, MEL-CSPG |
Calculated MW: | 251kDa |
Observed MW: | 251kDa |