NG2/CSPG4 Polyclonal Antibody (CAB21815)
- SKU:
- CAB21815
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | NG2/CSPG4 Polyclonal Antibody |
| Product Code: | CAB21815 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:7000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | U-138 MG |
| Cellular Location: | Apical cell membrane, Cell projection, Extracellular side, Single-pass type I membrane protein, lamellipodium membrane |
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1950-2210 of human NG2/CSPG4 (NP_001888.2). |
| Sequence: | LEVPQ ALGRS SLSQQ QLRVV SDREE PEAAY RLIQG PQYGH LLVGG RPTSA FSQFQ IDQGE VVFAF TNFSS SHDHF RVLAL ARGVN ASAVV NVTVR ALLHV WAGGP WPQGA TLRLD PTVLD AGELA NRTGS VPRFR LLEGP RHGRV VRVPR ARTEP GGSQL VEQFT QQDLE DGRLG LEVGR PEGRA PGPAG DSLTL ELWAQ GVPPA VASLD FATEP YNAAR PYSVA LLSVP EAART EAGKP ESSTP TGEPG PMASS PEPAV A |
| Synonyms: | NG2, MCSP, MCSPG, MSK16, CSPG4A, HMW-MAA, MEL-CSPG |
| Calculated MW: | 251kDa |
| Observed MW: | 250-450kDa |
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