Description
Product Name: | NG2/CSPG4 Monoclonal Antibody |
Product Code: | CAB24955 |
Reactivity: | Human |
Applications: | Immunohistochemistry, Immunofluorescence, Flow Cytometry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC64580 |
Reactivity: | Human |
Tested Applications: | IHC-P, IF/ICC, FC, ELISA |
Key Applications: | Immunohistochemistry, Immunofluorescence, Flow Cytometry |
Recommended Dilution: | IHC-P 1:50-1:200, IF/ICC 1:50-1:200, FC 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Cellular Location: | Apical cell membrane, Cell projection, Extracellular side, Single-pass type I membrane protein, lamellipodium membrane |
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1583-2224 of human NG2 (NP_001888.2). |
Sequence: | SLKGS QTLTV CPGSV QPLSS QTLRA SSSAG TDPQL LLYRV VRGPQ LGRLF HAQQD STGEA LVNFT QAEVY AGNIL YEHEM PPEPF WEAHD TLELQ LSSPP ARDVA ATLAV AVSFE AACPQ RPSHL WKNKG LWVPE GQRAR ITVAA LDASN LLASV PSPQR SEHDV LFQVT QFPSR GQLLV SEEPL HAGQP HFLQS QLAAG QLVYA HGGGG TQQDG FHFRA HLQGP AGASV AGPQT SEAFA ITVRD VNERP PQPQA SVPLR LTRGS RAPIS RAQLS VVDPD SAPGE IEYEV QRAPH NGFLS LVGGG LGPVT RFTQA DVDSG RLAFV ANGSS VAGIF QLSMS DGASP PLPMS LAVDI LPSAI EVQLR APLEV PQALG RSSLS QQQLR VVSDR EEPEA AYRLI QGPQY GHLLV GGRPT SAFSQ FQIDQ GEVVF AFTNF SSSHD HFRVL ALARG VNASA VVNVT VRALL HVWAG GPWPQ GATLR LDPTV LDAGE LANRT GSVPR FRLLE GPRHG RVVRV PRART EPGGS QLVEQ FTQQD LEDGR LGLEV GRPEG RAPGP AGDSL TLELW AQGVP PAVAS LDFAT EPYNA ARPYS VALLS VPEAA RTEAG KPESS TPTGE PGPMA SSPEP AVAKG GFLSF LEANM FS |
Synonyms: | NG2, MCSP, MCSPG, MSK16, CSPG4A, HMW-MAA, MEL-CSPG |
Calculated MW: | 251kDa |