Description
Antibody Name: | NFIA/NFIB/NFIC/NFIX Antibody |
Antibody SKU: | PACO04425 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from the N-terminal region of human NF-1. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | NFIA; KIAA1439; Nuclear factor 1 A-type; NF1-A; Nuclear factor 1/A; CCAAT-box-binding transcription factor; CTF; Nuclear factor I/A; NF-I/A; NFI-A; TGGCA-binding protein; NFIB; Nuclear factor 1 B-type; NF1-B; Nuclear factor 1/B; CCAAT-box-b |
UniProt Protein Function: | NFI-A: Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 1p31.3-p31.2 Cellular Component: nucleoplasm; nucleus; cell junction Molecular Function:transcription factor binding; transcription factor activity Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; viral genome replication; DNA replication; response to organic cyclic substance |
NCBI Summary: | This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
UniProt Code: | Q12857 |
NCBI GenInfo Identifier: | 14194959 |
NCBI Gene ID: | 4774 |
NCBI Accession: | Q12857.2 |
UniProt Secondary Accession: | Q12857,O00712, P08651, Q14938, |
UniProt Related Accession: | Q12857 |
Molecular Weight: | |
NCBI Full Name: | Nuclear factor 1 A-type |
NCBI Synonym Full Names: | nuclear factor I A |
NCBI Official Symbol: | NFIA |
NCBI Official Synonym Symbols: | CTF; NF1-A; NFI-A; NFI-L; BRMUTD; NF-I/A |
NCBI Protein Information: | nuclear factor 1 A-type |
UniProt Protein Name: | Nuclear factor 1 A-type |
UniProt Synonym Protein Names: | CCAAT-box-binding transcription factor; CTF; Nuclear factor I/A; NF-I/A; NFI-A; TGGCA-binding protein |
UniProt Gene Name: | NFIA |
UniProt Entry Name: | NFIA_HUMAN |