NFATC1 Monoclonal Antibody [PAT1C3AT] (CPAB0566)
![NFATC1 Monoclonal Antibody [PAT1C3AT] (CPAB0566)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58787/63969/nfatc1-monoclonal-antibody-pat1c3at-cpab0566__48814__13490.1706535217.jpg?c=1 "NFATC1 Monoclonal Antibody [PAT1C3AT] (CPAB0566)")
- SKU:
- CPAB0566
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT1C3AT
- Applications:
- WB
- Applications:
- ELISA
![NFATC1 Monoclonal Antibody [PAT1C3AT] (CPAB0566)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58787/63969/nfatc1-monoclonal-antibody-pat1c3at-cpab0566__48814__13490.1706535217.jpg?c=1&imbypass=on "NFATC1 Monoclonal Antibody [PAT1C3AT] (CPAB0566)")
Description
system_update_alt Datasheet
| Product Name: | NFATC1 Antibody |
| Product Sku: | CPAB0566 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human NFATC1 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NFATC1 amino acids 428-716 purified from Ecoli. |
| Clone: | PAT1C3AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | NFATC1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2a |
| Background: | NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least 2 components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play an essential role in inducible gene transcription during immune response. NFATC1 is an inducible nuclear component. NFATC1 functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of NFATC1 may regulate inducible expression of different cytokine genes. |
| Synonyms: | Nuclear factor of activated T-cells cytoplasmic 1, NFAT transcription complex cytosolic component, NF-ATc1, NFATc1, NF-ATc, NFATc, NFAT2, MGC138448. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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